Dec
29How Acids and Their Derivatives Promote Liver Health
Filed Under (What Does The Liver Do: Health Tips) by admin on 29-12-2008
Tagged Under : Acids, hepatitis, liver health
The main acids and their derivatives that promote liver health are branched-chain amino acids like valine, leucine, isoleucine, arginine, ornithine, aspartate, S-adenosylmethionine.
There exist several ways to use branched-chain amino acids to promote liver health. When serious pathologic disorders happen, they damage hepatobiliary system and oxidation activity of the main energy sources decreases. This leads to a lack of the main substrates in the human body, as only 30-40 % of vital energy can oxidize by means of amino acids oxidation in other organs and tissues.
Meanwhile, protein catabolism increases and body weight with sick people decreases intensively. On the other hand, in the course of liver disease, concentration of aromatic amino acids in blood plasma increases which leads to various central nervous system diseases and portal systemic encephalopathy. Introduction of branched-chain amino acids removes imbalance, benefits those suffering from portal systemic encephalopathy and promotes liver health in general. Branched-chain amino acids can promote protein synthesis in muscles and liver, can reduce its catabolism thus decreasing negative nitrogen balance. Leucine is produced by Kupffer cells which proves direct influence of branched-chain amino acids on tissue cells.
Let’s consider some branched-chain amino acids that promote liver health.
Arginine is characterized by a great protecting power when different liver diseases develop. First of all, this amino acid plays a leading role in nitrogen metabolism contributing to the urea cycle. Therefore, arinine use is rather important for treatment of different liver diseases that are normally accompanied by its detoxicative function. Particularly, at viral hepatitis, arginine benefits immune system increasing number of T- lymphocytes and their functional activity.
Ornithine and aspartate function in the same way as arginine does. They enhance liver detoxicative function by entering the urea cycle. Moreover, aspartate can bind ammonia in organs and tissues, mainly in liver and brain, through glutamine synthesis.
You are welcome to read the general health tips that follow to learn more about bioactive substances that promote liver health.
